Organized Bio-Modules (OBM) using Microorganisms

Concept

Our goal is the realization of a super-large-scale microsystem that provides flexible and various functions, by integrating microorganisms as modules into information processing systems. For existing Micro-Electro Mechanical System (MEMS), it has been difficult to sense the status of the system. Therefore it provides only a single function. However, microorganisms are very smart micromachines with built-in sensors and actuators in their bodies. By feedback control system which makes many microorganisms cooperate together, a novel programmable and multi-functional microsystem will be realized. Our technologies, such as Visual Servoing Theory, Microscopic Visual Feedback (MVF) System and High-speed Focusing Lens, will be applied effectively to the OBM system.

References (in English)

1. Naoko Ogawa, Hiromasa Oku, Koichi Hashimoto and Masatoshi Ishikawa. Trajectory Planning of Motile Cell for Microrobotic Applications. Journal of Robotics and Mechatronics, Vol.19, No.2, pp.190-197, Apr. 2007. [abstract]
2. Naoko Ogawa, Hiromasa Oku, Koichi Hashimoto and Masatoshi Ishikawa. A physical model for galvanotaxis of Paramecium cell. Journal of Theoretical Biology, Vol.242, Issue 2, pp.314-328, Sept. 2006. [PDF (484K)][doi:10.1016/j.jtbi.2006.02.021]^*Elsevier
3. Anchelee Davies, Naoko Ogawa, Hiromasa Oku, Koichi Hashimoto and Masatoshi Ishikawa. Visualization and Estimation of Contact Stimuli using Living Microorganisms. 2006 IEEE International Conference on Robotics and Biomimetics (ROBIO 2006) (Kunming, China, 18 Dec 2006) / Proceedings, pp. 445-450, Dec. 2006. (Best Paper in Biomimetics) [PDF (317K)] ^*IEEE
4. Naoko Ogawa, Hiromasa Oku, Koichi Hashimoto and Masatoshi Ishikawa. Dynamics Modeling and Real-Time Observation of Galvanotaxis in Paramecium caudatum toward Robotic Maneuvering. The 3rd International Symposium on Aero Aqua Bio-mechanisms (ISABMEC 2006) (Okinawa, Japan, 5 Jul 2006) / Proceedings, P02, Jul. 2006. [PDF (375K)]
5. Naoko Ogawa, Hiromasa Oku, Koichi Hashimoto and Masatoshi Ishikawa. Evaluation and Suppression of Overrun of Microorganisms using Dynamics Model for Microrobotic Application. 9th International Conference on Intelligent Autonomous Systems (IAS-9) (Kashiwa, Japan, 2006.3.8) / Intelligent Autonomous Systems 9 (T. Arai et al. Eds.), pp. 1015-1024, IOS Press, Mar. 2006. [PDF (358K)]
6. Naoko Ogawa, Hiromasa Oku, Koichi Hashimoto and Masatoshi Ishikawa. Microrobotic Visual Control of Motile Cells using High-Speed Tracking System. IEEE Transactions of Robotics, Vol. 21, No. 4, pp. 704-712, Aug. 2005. [PDF (1.1M)][doi:10.1109/TRO.2005.844686] ^*IEEE
7. Naoko Ogawa, Hiromasa Oku, Koichi Hashimoto and Masatoshi Ishikawa. Microrobotic Control of Paramecium Cells using Galvanotaxis. 2005 IEEE International Conference on Robotics and Biomimetics (ROBIO 2005) (Macau, China, 2005.7.3) / ROBIO'05 Workshop on Biomimetic Robotics and Biomimetic Control, pp. 23-35, Jul. 2005. [PDF (3.1M)]
8. Naoko Ogawa, Hiromasa Oku, Koichi Hashimoto and Masatoshi Ishikawa. Dynamics Model of Paramecium Galvanotaxis for Microrobotic Application. 2005 IEEE International Conference on Robotics and Automation (ICRA 2005) (Barcelona, Spain, 2005.4.19) / Proceedings, pp. 1258-1263, Apr. 2005. [PDF (341K)] ^*IEEE
9. Naoko Ogawa, Hiromasa Oku, Koichi Hashimoto and Masatoshi Ishikawa. Motile Cell Galvanotaxis Control using High-Speed Tracking System. 2004 IEEE International Conference on Robotics and Automation (ICRA 2004) (New Orleans, USA, 2004.4.28) / Proceedings, pp. 1646-1651, Apr, 2004. [PDF (1.7M)] ^*IEEE
10. Naoko Ogawa, Hiromasa Oku, Koichi Hashimoto and Masatoshi Ishikawa. Single-Cell Level Continuous Observation of Microorganism Galvanotaxis using High-Speed Vision. 2004 IEEE International Symposium on Biomedical Imaging (ISBI 2004) (Arlington, VA, USA, 2004.4.18) / Proceedings, pp. 1331-1334, Apr. 2004. [PDF (982K)] ^*IEEE